Sitki Cem Parlar

GBAviewer maps GBA1 variants onto GCase structures to aid in understanding their structural impact on Parkinson's disease.

This study examines the association between PGK1 variants and Parkinson's disease but finds no evidence of such a link in large cohorts.

The paper investigates the genetic role of SLC25A46 in Parkinson's disease, REM sleep behavior disorder, and Dementia with Lewy Bodies, finding no significant associations.

This study investigates the genetic role of SLC7A11 in Parkinson's Disease using whole-genome sequencing data and finds no association between SLC7A11 variants and PD risk or GCase activity.

This study finds the GBA1 p.E427K variant increases risk for synucleinopathies through a meta-analysis of case-control studies.

The paper integrates machine learning and rare variant burden analysis to identify novel candidate genes for Parkinson's disease.

This study investigates ANO6's role in Parkinson's disease by analyzing common and rare variants across large datasets, finding no strong genetic association.

The paper assesses the contribution of unknown GBA1 variants to Parkinson's disease risk and their relevance for clinical trial stratification.

This study investigates the association between G6PD variants and Parkinson's disease across six cohorts and finds no significant links for common or rare variants.

This study investigates the association between rare SYNJ1 variants and Parkinson's disease, finding an association with both sporadic and early-onset cases.

The paper creates a database and browser for GBA1 variants associated with Parkinson's Disease, classifying them into severe, mild, and risk categories.