Author

Diksha Rathore

Indian Institute of Science BangaloreORCID 0009-0004-2082-3044Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:rat· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Sathees C. RaghavaniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 26, 2025

Mitochondrial G4 DNA Cleavage by EndoG Activates a Flexible, Stress-Dependent Repair Response via Double strand break repair pathways

Diksha Rathore, Sathees C. Raghavan

The paper identifies a stress-dependent mitochondrial DNA repair mechanism involving EndoG-induced double-strand breaks resolved by MMEJ and HR.

DOI 10.1101/2025.08.26.672151

DNA methylationstatistical model

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJun 13, 2025

Tissue-Specific Activation of Microhomology-Mediated End Joining with Age Reflects Dynamic Rewiring of DNA Repair in Rats

This study shows that MMEJ activity changes with age and varies by tissue in rats, with implications for genomic instability and potential therapeutic targets.

DOI 10.1101/2025.06.13.659285

ratexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMay 23, 2025

Context-Dependent Regulation of Microhomology-Mediated End Joining in Normal Tissues: Insights into Tissue-Specific Activation of DNA Repair Pathways

The paper shows MMEJ is selectively active in proliferative tissues and suppressed in post-mitotic tissues, with implications for genomic stability and therapy.

DOI 10.1101/2025.05.23.653089

humanstatistical model

𝕏 PostBluesky