Molecular BiologyJournal of BacteriologyPeer-reviewed
An unusual activity of mycobacterial MutT1 Nudix hydrolase domain as a protein phosphatase regulates nucleoside diphosphate kinase (NDK) function
Elhassan Ali Fathi Emam, Koyel Roy, Devendra Pratap Singh…·Umesh Varshney
This paper shows that mycobacterial MutT1, through its Nudix hydrolase domain, functions as a protein phosphatase to regulate NDK-Pi levels and prevent the conversion of 8-oxo-dGDP to 8-oxo-dGTP, thereby reducing A to C mutations.
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