Umesh Varshney

The paper shows that tRNAs can form complementary pairs, leading to sequestration of rare tRNAs and affecting bacterial growth and phage replication.

This study shows Salmonella Typhimurium uses AI-2 quorum sensing to enhance acid tolerance and survival in macrophages by modulating pH-sensing systems and SPI-2 regulators.

The paper identifies MutT1 as a phosphatase that dephosphorylates sensor kinases in Mycobacterium tuberculosis, revealing a new regulatory mechanism in two-component signaling.

This paper shows that mycobacterial MutT1, through its Nudix hydrolase domain, functions as a protein phosphatase to regulate NDK-Pi levels and prevent the conversion of 8-oxo-dGDP to 8-oxo-dGTP, thereby reducing A to C mutations.