Evolutionary BiologybioRxivPreprint
Narrowed host ranges do not constrain future host range expansion in RNA phage phi6
Taylor P. Andrews, Abbey Isaac, Siobain Duffy
This study shows that RNA phage phi6 specialists can re-expand their host ranges through mutations, including reversion of narrowing mutations or parallel mutations, indicating no constraint from their mutational backgrounds.
DOI 10.1101/2025.05.12.653482