GenomicsComputational and Structural Biotechnology JournalPeer-reviewed
Unbiased Long-Read Whole-Genome Sequencing Enables High-Resolution Mapping of Transgene Concatenation and Off-target Genomic Disruption in a Mouse Model
Maanik Mehta, Kashif Ahmed, Rowaida Hussein…·Ajoy Vincent
The paper uses long-read sequencing to detect transgene concatenation and off-target integration in a mouse model, revealing hidden genomic complexity and phenotypic disruption.
DOI 10.34133/csbj.0234