Erika Sendra Tavares

The paper uses long-read sequencing to detect transgene concatenation and off-target integration in a mouse model, revealing hidden genomic complexity and phenotypic disruption.

This study shows RPGR variants impair motile cilia in airway multiciliated cells by causing apical F-actin accumulation, leading to reduced ciliation, shorter cilia, and impaired cilia beat.

This study identifies epigenomic anomalies in iPSCs derived from Alzheimer's disease patients that affect neural differentiation and amyloid/Tau pathology.