Author

Thérence Bois

Montreal Clinical Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1

Frequent Co-Authors

Andrew J. WedlakeiD· 1 shared Christine JolicoeuriD· 1 shared David ErringtoniD· 1 shared Deniz DalkaraiD· 1 shared Emmanuel BengioiD· 1 shared Francesco Di GiovanniiD· 1 shared Jenny Cai· 1 shared Kacper KapusniakiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andrew J. WedlakeORCID

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2 papers

Recent·Most cited

Nesso-1: Accelerating Open-Source Binding Affinity Predictions

Nikhil Shenoy, David Errington, Emmanuel Bengio, Kacper Kapusniak, Kerstin Kläser, Yui Tik Pang, Vladimir Radenkovic, Prudencio Tossou, Thérence Bois, Andrew J. Wedlake, Francesco Di Giovanni

Nesso-1 is an open-source binding affinity prediction tool that is significantly faster than Boltz-2 while maintaining or improving accuracy on both in-distribution and out-of-distribution data.

bioRxiv · Aug 3, 2026 · PreprintMolecular Biology

Numb reduces Tau levels and prevents neurodegeneration in mouse models of tauopathy in an isoform-specific manner

Marine Lacomme, Sarah C. Hales, Thomas W. Brown, Katarina Stevanovic, Christine Jolicoeur, Jenny Cai, Thérence Bois, Mélissa Desrosiers, Deniz Dalkara, Michel Cayouette

This study shows that Numb regulates Tau levels and prevents neurodegeneration in tauopathy models, with Numb-72 specifically reducing intracellular Tau.

Science Advances · Oct 19, 2022Peer-reviewedNeuroscience