Author

Donald Kramer

Johns Hopkins UniversityORCID 0009-0004-3381-119XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:spatial domain detection· 2 Assay:spatial transcriptomics· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

André ForjaziD· 3 shared Ashley L. KiemeniD· 3 shared Denis WirtziD· 3 shared Habin BeaiD· 2 shared Luciane Tsukamoto KagoharaiD· 2 shared Margarita Tsapatsis· 2 shared Mark A. AtkinsoniD· 2 shared Saurabh JoshiiD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersBioinformatics

André ForjazORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 21, 2025

3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursors

André Forjaz, Vasco Queiroga, Yajuan Li…·Denis Wirtz

The paper presents a 3D multi-omic framework to detect and characterize ovarian cancer precursors in fallopian tubes, identifying TP53 mutations in microscopic lesions.

4 citations

humanspatial transcriptomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJun 8, 2025

PIVOT: an open-source tool for multi-omic spatial data registration

André Forjaz, Valentina Matos-Romero, Ian Reucroft…·Ashley L. Kiemen

PIVOT is an open-source tool for nonlinear registration of multi-omic spatial data, demonstrating improved throughput compared to existing workflows.

4 citations

spatial transcriptomicsexperimental assay

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 31, 2025

Integration of nuclear morphology and 3D imaging to profile cellular neighborhoods

André Forjaz, Donald Kramer, Yu Shen…·Denis Wirtz

The paper integrates 3D imaging with nuclear segmentation to analyze nuclear morphology in human tissue, revealing spatial patterns and interactions in disease progression.

5 citations

humanimaging

𝕏 PostBluesky