Habin Bea

This study shows chronic alcohol exposure leads to inflammation, DNA damage, and transposon activation in hematopoietic stem and progenitor cells, with lasting effects on myeloid bias and immune responses.

The paper presents a 3D multi-omic framework to detect and characterize ovarian cancer precursors in fallopian tubes, identifying TP53 mutations in microscopic lesions.

The paper identifies ALDH9A1 deficiency as a source of endogenous DNA damage that requires FA pathway repair, leading to genomic instability and tumorigenesis in FA-deficient cells.

The paper integrates 3D imaging with nuclear segmentation to analyze nuclear morphology in human tissue, revealing spatial patterns and interactions in disease progression.