Molecular BiologybioRxivPreprint
Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at ER monitoring and regulating fatty acids
Song‐iee Han, Masanori Nakakuki, Yoshimi Nakagawa…·Hitoshi Shimano
The paper shows RHBDL4 cleaves SREBP-1c at the ER, with its activity modulated by fatty acid types, and demonstrates its role in lipid homeostasis.
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