Neurosciencenpj Parkinson s DiseasePeer-reviewed
G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage
Nicholas Pena, Tara Richbourg, Claudia P. González-Hunt…·Laurie H. Sanders
The paper tests a G2019S selective LRRK2 inhibitor, EB-42168, showing it reduces mtDNA damage in G2019S models and patient cells better than a non-selective inhibitor.
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