Author

Rui Qi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Dong Wang· 1 shared Hua CheniD· 1 shared Hui Bao· 1 shared Juan Li· 1 shared Kai LviD· 1 shared Kequan Lin· 1 shared Lu Han· 1 shared Ming Yang· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Dong Wang

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Segmented poly(A) tails with microRNA target sites confer tissue-specific regulation for mRNA therapeutics

Rui Qi, Hua Chen, Hui Bao, Ying Sun, Ruiwen Xu, Lu Han, Yingmei Xu, Juan Li, Na Li, Qiang Li, Tingting Zhang, Kai Lv, Yijie Dong, Shan Cen, Weiguo Zhang

This study engineers segmented poly(A) tails with microRNA target sites to enable tissue-specific regulation of mRNA-LNPs, showing position-dependent expression control in vitro and in vivo.

Molecular Therapy — Nucleic Acids · Sep 8, 2026Peer-reviewedBioengineering

Epigenetic Reprogramming of Tissue-Specific Transcription Promotes Metastasis

Shuaishuai Teng, Yang Li, Ming Yang, Rui Qi, Yiming Huang, Qianyu Wang, Shasha Li, Kequan Lin, Yujing Cheng, Zhi John Lu, Dong Wang

This study shows that epigenetic reprogramming of tissue-specific transcription in cancer cells promotes metastasis, with FOXA2 playing a key role in liver colonization by metastatic colorectal cancer cells.

bioRxiv · Apr 26, 2017 · PreprintCancer Biology