Author

Aleksandr A. Grachev

Kurchatov InstituteORCID 0009-0004-5566-651XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:protein structure· 1

Frequent Co-Authors

Alena PaleskavaiD· 2 shared Andrey L. KonevegaiD· 2 shared Olga A. TolichevaiD· 2 shared Сергиев Петр ВладимировичiD· 2 shared Alexei LivenskyiiD· 1 shared Alexey E. TupikiniD· 1 shared Anastasiia O. KarakchievaiD· 1 shared Arina A. NikandrovaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Alena PaleskavaORCID

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2 papers

Recent·Most cited

Molecular BiologyBiochemistry (Moscow)Peer-reviewedNov 1, 2025

Insights into the bottromycin A2 mechanism of action

Inna A. Volynkina, Aleksandr A. Grachev, Alexei Livenskyi…·Olga A. Dontsova

This paper identifies a novel mechanism by which Bottromycin A2 inhibits bacterial translation through context-specific ribosome stalling at glycine codons.

2 citations

experimental assay

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Molecular BiologyNucleic Acids ResearchPeer-reviewedDec 22, 2022

Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.

Madhura N. Paranjpe, Valeria I. Marina, Aleksandr A. Grachev…·Matthieu G. Gagnon

This paper investigates how thermorubin inhibits translation by causing ribosome stalling and affecting tRNA binding and translation elongation.

12 citations

bacteria (other)protein structure

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