Author

Marc Altorfer

Novartis (Switzerland)ORCID 0009-0004-6074-5087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Alejandro ReyesiD· 2 shared Christian KolteriD· 2 shared Judith KnehriD· 2 shared Alexander Bepperling· 1 shared Alexandra Vissières· 1 shared Amanda Cobos‐Correa· 1 shared Amandine Rietsch· 1 shared Andrea Byrnes· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Alejandro ReyesORCID

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3 papers

Recent·Most cited

Molecular BiologyDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJul 1, 2026

Specificity and exon target space of splicing modifying compounds

Felina Lenkeit, Judith Knehr, Marc Altorfer…·Alejandro Reyes

This study investigates the specificity of splicing modulators by analyzing their interactions with RNA structures and demonstrates reprogramming of their specificity through genetic manipulation of the spliceosome.

DOI 10.1038/s41467-026-74594-9

humanbulk RNA-seq

PhysiologybioRxivPreprintApr 9, 2025

Exercise-Induced Myostimulin Enhances Muscle Function in Health and Disease

Frank Hillger, Keller Hansjörg, Angela Furrer…·Serge Summermatter

This study identifies myostimulin, a protein derived from C1ORF54, which enhances muscle function and recovery in mice, suggesting its potential as a therapeutic for musculoskeletal diseases.

DOI 10.1101/2025.04.09.647960

mousebulk RNA-seq

Molecular BiologyJCI InsightPeer-reviewedFeb 25, 2025

The transcription factor ZNF469 regulates collagen production in liver fibrosis

Sebastian Steinhauser, David Estoppey, Dennis P. Buehler…·Christian Kolter

The paper identifies ZNF469 as a transcription factor regulating collagen production in liver fibrosis through computational analysis and experimental validation.

10 citationstop 5%

humanbulk RNA-seq