Author

Christian Kolter

Novartis (Switzerland)ORCID 0000-0001-5174-6126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Alejandro ReyesiD· 3 shared Judith KnehriD· 2 shared Marc AltorferiD· 2 shared Sebastian SteinhauseriD· 2 shared Alexandra Vissières· 1 shared Amandine Rietsch· 1 shared Andrea Byrnes· 1 shared Andrew T. Krueger· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

Alejandro ReyesORCID

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3 papers

Recent·Most cited

Molecular BiologyDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJul 1, 2026

Specificity and exon target space of splicing modifying compounds

Felina Lenkeit, Judith Knehr, Marc Altorfer…·Alejandro Reyes

This study investigates the specificity of splicing modulators by analyzing their interactions with RNA structures and demonstrates reprogramming of their specificity through genetic manipulation of the spliceosome.

DOI 10.1038/s41467-026-74594-9

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologyJCI InsightPeer-reviewedFeb 25, 2025

The transcription factor ZNF469 regulates collagen production in liver fibrosis

Sebastian Steinhauser, David Estoppey, Dennis P. Buehler…·Christian Kolter

The paper identifies ZNF469 as a transcription factor regulating collagen production in liver fibrosis through computational analysis and experimental validation.

10 citationstop 5%

humanbulk RNA-seq

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BioinformaticsComputational and Structural Biotechnology JournalPeer-reviewedMay 11, 2024

Benchmarking tools for transcription factor prioritization

Leonor Schubert Santana, Alejandro Reyes, Sebastian Hoersch…·Sebastian Steinhauser

This study benchmarks nine TF prioritization tools using H3K27ac ChIP-seq data from 84 perturbation experiments, identifying three top-performing tools.

5 citations

ChIP-seqbenchmark study

𝕏 PostBluesky