Author

Yun Hao

Simons FoundationORCID 0009-0004-6198-3060Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Chandra T Theesfeld· 1 shared Christopher Y. ParkiD· 1 shared Olga G. TroyanskayaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperGenomics

Chandra T Theesfeld

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintOct 11, 2026

Spatiotemporal AI modeling of gene regulation and variant effects in the developing human brain

Yun Hao, Christopher Y. Park, Chandra T Theesfeld, Olga G. Troyanskaya

This paper introduces Seal, an AI framework that models gene regulation and variant effects in the developing human brain across multiple regions, cell types, and stages, identifying regulatory mechanisms linked to neuropsychiatric diseases.

DOI 10.64898/2026.10.09.757610

humanwhole-genome sequencing

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