PathologyFree Radical Biology and MedicinePeer-reviewed
Systemic aldehyde storm induced by allyl alcohol exposure results in extensive hepatic ferroptosis in Aldh2*2 knock-in mice
Yuki Takami, Jun Nakamura, Jun Katahira…·Takeshi Izawa
This study shows that Aldh2*2 knock-in mice exposed to allyl alcohol experience a systemic aldehyde storm leading to hepatic ferroptosis due to impaired aldehyde detoxification.
5 citations