In vivo Targeting MEK and TNK2/SRC pathways in PTPN11 driven leukemia
Bill H. Chang, Karina Thiel-Klare, Jeffrey W. Tyner
This study shows that combining MEK and TNK2/SRC inhibitors effectively treats PTPN11-mutant leukemias in mouse models and patient-derived xenografts.
bioRxiv · May 16, 2024 · PreprintCancer Biology