Cancer BiologybioRxivPreprint
In vivo Targeting MEK and TNK2/SRC pathways in PTPN11 driven leukemia
Bill H. Chang, Karina Thiel-Klare, Jeffrey W. Tyner
This study shows that combining MEK and TNK2/SRC inhibitors effectively treats PTPN11-mutant leukemias in mouse models and patient-derived xenografts.
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