Author

Anja Spieler

University Hospital HeidelbergORCID 0009-0004-6831-0707Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Chiara HessiD· 1 shared Christian Albert GleissneriD· 1 shared Florian LeuschneriD· 1 shared Florian SicklingeriD· 1 shared Hugo Albert KatusiD· 1 shared Jona Benjamin KrohniD· 1 shared Julie Kawohl· 1 shared Larissa Eis· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Chiara HessORCID

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1 paper

Recent·Most cited

ImmunologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedAug 21, 2025

CXCL4-induced PBMCs Modulate Vascular Extracellular Matrix through Wnt5a-dependent Release of Calcific Extracellular Vesicles and Matrix Metalloproteinase-7

Jona Benjamin Krohn, Laurine Kristin Sprehe, Florian Sicklinger…·Florian Leuschner

This study identifies a novel mechanism by which CXCL4-induced monocytes release calcific extracellular vesicles and MMP7 to modulate vascular extracellular matrix through Wnt5a-CaMKII signaling.

9 citations

humanbulk RNA-seq

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