Edited Filamin A in myeloid cells reduces intestinal inflammation and protects from colitis
Riem Gawish, Rajagopal Varada, Florian Deckert, Anastasiya Hladik, Linda Steinbichl, Laura Cimatti, Katarina Milanovic, Mamta K Jain, Natalya Torgasheva, Andrea Tanzer A, Kim De Paepe, Tom Van de Wiele, Bela Hausmann, Michaela Lang, Martin Pechhacker, , Cornelia Vesely
This study shows that RNA editing of FLNA in myeloid cells reduces intestinal inflammation and protects against colitis in mice and humans.
bioRxiv · Mar 25, 2025 · PreprintMolecular Biology