Author

Hanako Ono

National Cancer Center Research InstituteORCID 0009-0004-7697-9849Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Daichi NarushimaiD· 1 shared Daisuke ShiokawaiD· 1 shared Eisaku Furukawa· 1 shared Hiromi K. NakamuraiD· 1 shared Koji OkamotoiD· 1 shared Koshi MimoriiD· 1 shared Mamoru KatoiD· 1 shared Momoko Nagai· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Daichi NarushimaORCID

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1 paper

Recent·Most cited

Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model

Hanako Ono, Yasuhito Arai, Eisaku Furukawa, Daichi Narushima, Tetsuya Matsuura, Hiromi K. Nakamura, Daisuke Shiokawa, Momoko Nagai, Toshio Imai, Koshi Mimori, Koji Okamoto, Yoshitaka Hippo, Tatsuhiro Shibata, Mamoru Kato

This study uses single-cell DNA and RNA sequencing to analyze intra-tumor heterogeneity dynamics in a mouse colorectal cancer model, finding increased RNA heterogeneity and decreased DNA heterogeneity after transplantation.

BMC Biology · Sep 21, 2021Peer-reviewedGenomics