Author

Yoshitaka Hippo

Chiba Cancer Center Research InstituteORCID 0000-0002-4975-1812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Atsushi YamadaiD· 1 shared Daichi NarushimaiD· 1 shared Daisuke HoshiiD· 1 shared Daisuke ShiokawaiD· 1 shared Eisaku Furukawa· 1 shared Hanako OnoiD· 1 shared Hiromi K. NakamuraiD· 1 shared Hiroyuki Uematsu· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Atsushi YamadaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

IGF2BP3 is essential for the growth heterogeneity of colorectal adenoma cells by regulating MYC

Tomohiko Sunami, Roberto Coppo, Kunishige Onuma, Jumpei Kondo, Hiroyuki Uematsu, Daisuke Hoshi, Yoshihiro Yamamoto, Osamu Kikuchi, Shinya Ohashi, Yasuhide Takeuchi, Kazuto Kugou, Yoshinori Hasegawa, Yoshiro Itatani, Kazutaka Obama, Yoshitaka Hippo, , Masahiro Inoue

The paper identifies IGF2BP3 as a regulator of MYC that contributes to growth heterogeneity in colorectal adenoma cells through both transcriptional and translational mechanisms.

iScience · Jun 26, 2026Peer-reviewedCancer Biology

Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model

Hanako Ono, Yasuhito Arai, Eisaku Furukawa, Daichi Narushima, Tetsuya Matsuura, Hiromi K. Nakamura, Daisuke Shiokawa, Momoko Nagai, Toshio Imai, Koshi Mimori, Koji Okamoto, Yoshitaka Hippo, Tatsuhiro Shibata, Mamoru Kato

This study uses single-cell DNA and RNA sequencing to analyze intra-tumor heterogeneity dynamics in a mouse colorectal cancer model, finding increased RNA heterogeneity and decreased DNA heterogeneity after transplantation.

BMC Biology · Sep 21, 2021Peer-reviewedGenomics