Asfar Lathif Salaudeen

The paper benchmarks 12 base editors delivered via VLPs for DNA editing in LentiX-293T cells, showing dosage-dependent efficiency and varying mutation outcomes.

This paper introduces a method to rapidly construct gRNA arrays for CRISPR-Cas9 applications and provides a web tool for designing oligo sequences.

The paper quantifies the gene regulatory activity of naive DNA in yeast and human cells, finding that naive DNA can produce transcripts and chromatin marks similar to evolved sequences, suggesting biochemical activity is the default state.

GIL designs custom indexing primers for multiplexed sequencing, offering customization and compatibility with existing primers.