Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
Catia Mota, Kiseung Kim, Ye Ji Son, Eun Jung Thak, Su‐Bin Lee, Ju-El Kim, Jeong‐Kee Yoon, Min‐Ho Kang, Heeyoun Hwang, Yong‐Sun Bahn, J. Andrew Alspaugh, Hyun Ah Kang
This study investigates the role of an N-glycan-dependent ERQC system in C. neoformans, showing its impact on virulence, cell surface organization, and extracellular vesicle transport.
eLife · May 27, 2025Peer-reviewedMicrobiology