J. Andrew Alspaugh

This paper identifies a cysteine-rich motif in CnCuf1 essential for high copper stress sensing in Cryptococcus neoformans, impacting fungal virulence and lung infection patterns.

This study shows that Rsp5 ubiquitination regulates trehalose biosynthesis in C. neoformans, enhancing thermotolerance and salt stress resistance.

This study investigates the role of an N-glycan-dependent ERQC system in C. neoformans, showing its impact on virulence, cell surface organization, and extracellular vesicle transport.

This study identifies the Rim/Pal pathway in Malassezia sympodialis as essential for alkaline pH adaptation and demonstrates its role in atopic dermatitis.

CryptoCEN, a co-expression network for Cryptococcus neoformans, identifies 13 novel DNA damage repair genes with 100% predictive accuracy.

This study identifies genetic pathways in Cryptococcus neoformans that contribute to tolerance of the antifungal drug caspofungin.