Author

Francisca J Bergsma

Princess Máxima CenterORCID 0009-0004-8765-4732Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Judith WienkeiD· 2 shared Anne L. BorstiD· 1 shared Arjan BoltjesiD· 1 shared Bob Baalman· 1 shared Daniëlle KrijgsmaniD· 1 shared Femke van den Ham· 1 shared Francis MussaiiD· 1 shared Hubert N. CaroniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Judith WienkeORCID

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2 papers

Recent·Most cited

Inhibitory Nectin-2/TIGIT interactions between CD163+ macrophages and CD8+ T cells in spatially defined immune niches associate with poor outcomes in neuroblastoma

Anne L. Borst, Francisca J Bergsma, Femke van den Ham, Meggy E.L. Verdonschot, Mojtaba Amini, Arjan Boltjes, Stephanie van Dam, Naima Hiddink Verberne, Noah Bonine, Jeanette H.W. Leusen, Max Maria van Noesel, Ronald R. de Krijger, Yvonne Vercoulen, Daniëlle Krijgsman, Judith Wienke

The paper identifies inhibitory Nectin-2/TIGIT interactions between CD163+ macrophages and CD8+ T cells in neuroblastoma tumor niches, linking them to poor patient outcomes.

bioRxiv · Oct 8, 2026 · PreprintCancer Biology

The immune landscape of pediatric Brain and Solid Tumors: A systematic review and integration of immunohistochemistry and single-cell RNA sequencing data

Francisca J Bergsma, Jan Köster, Bob Baalman, Francis Mussai, Hubert N. Caron, Jan J. Molenaar, Judith Wienke

This study integrates immunohistochemistry and single-cell RNA sequencing data to characterize the immune landscape of pediatric brain and solid tumors, revealing distinct immune microenvironment features across tumor types.

bioRxiv · Jun 6, 2025 · PreprintImmunology