Author

Femke van den Ham

Princess Máxima Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell-cell communication· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Approach:microscopy & imaging analysis· 1 Assay:multiome· 1

Frequent Co-Authors

Judith WienkeiD· 3 shared Arjan BoltjesiD· 2 shared Jan J. MolenaariD· 2 shared John AndersoniD· 2 shared Naima Hiddink VerberneiD· 2 shared Ailsa Greppi· 1 shared Alice VitaliiD· 1 shared Anne C. RiosiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Judith WienkeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 8, 2026

Inhibitory Nectin-2/TIGIT interactions between CD163+ macrophages and CD8+ T cells in spatially defined immune niches associate with poor outcomes in neuroblastoma

Anne L. Borst, Francisca J Bergsma, Femke van den Ham…·Judith Wienke

The paper identifies inhibitory Nectin-2/TIGIT interactions between CD163+ macrophages and CD8+ T cells in neuroblastoma tumor niches, linking them to poor patient outcomes.

DOI 10.64898/2026.10.07.756693

humanspatial transcriptomics

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Cancer BiologybioRxivPreprintDec 3, 2025

Proteomic profiling of the neuroblastoma secretome identifies extracellular vesicles as drivers of T cell suppression

Josephine G. M. Strijker, Ronja E. van Berkum, Elisavet Kalaitsidou…·Judith Wienke

The paper identifies extracellular vesicles as immunosuppressive factors in neuroblastoma by profiling secretomes and showing their ability to suppress T cell activation.

DOI 10.64898/2025.12.02.690421

humanproteomics

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BioengineeringNature CommunicationsPeer-reviewedAug 5, 2025

Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function

Marta Barisa, Henrike P. Muller, Elisa Zappa…·John Anderson

The paper evaluates how the functional avidity of anti-B7H3 CAR-T constructs relates to their ability to trigger effector function against tumors with varying antigen density.

29 citationstop 1%

humanflow cytometry

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