Robert S. Negrin

This paper develops TGF-β agonists targeting specific T and B cells to selectively suppress pathogenic immune responses in autoimmune and inflammatory diseases.

This study uses single-cell RNA-sequencing to analyze human iNKT cells from multiple tissues, identifying novel transcriptional patterns and subsets not previously described in mice.

This study demonstrates that gene-corrected human airway stem cells can durably engraft and restore CFTR function in murine respiratory epithelium, offering a potential therapy for cystic fibrosis.