Author

Alex D. Botha

University of OtagoORCID 0009-0004-9443-0091Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Organism:zebrafish· 1

Frequent Co-Authors

Aakriti Sethi· 1 shared Christoph GöbliD· 1 shared Grant Greene· 1 shared Hannah DarrochiD· 1 shared Julia Horsfield· 1 shared Karina M. O'Connor· 1 shared Nicholas J. MagoniD· 1 shared Pierre de Cordovez· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aakriti Sethi

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1 paper

Recent·Most cited

Hierarchical cysteine oxidation controls reversible amyloid formation in an ankyrin repeat protein

Aakriti Sethi, Hannah Darroch, Nicholas J. Magon, Grant Greene, Karina M. O'Connor, Alex D. Botha, Shelby G. Gray, Pierre de Cordovez, Rachel Coldicott, Julia Horsfield, Vanessa K. Morris, Christoph Göbl

This paper shows that cysteine oxidation in drP18 controls reversible amyloid formation, with distinct oxidants leading to different amyloid kinetics and morphologies.

bioRxiv · Sep 3, 2026 · PreprintBiochemistry