Author

Antonino Napoleone

Austrian Centre of Industrial Biotechnology (Austria)ORCID 0009-0004-9552-2465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Alexander Molin· 2 shared Federico De MarcoiD· 2 shared Ivy Rose SebastianiD· 2 shared Lovro KrameriD· 2 shared Nicole BorthiD· 2 shared Thomas Jostock· 2 shared Krishna MotheramgariiD· 1 shared Markus RiedliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMolecular Biology

Alexander Molin

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2 papers

Recent·Most cited

Overcoming lentiviral delivery limitations in hard-to-transduce suspension cells for genome-wide CRISPR screening

Antonino Napoleone, Ivy Rose Sebastian, Federico De Marco, Alexander Molin, Mohamed Hussein, Lovro Kramer, Thomas Jostock, Thomas Kelly, Nicole Borth

This study improves lentiviral transduction efficiency in suspension cells for CRISPR screening by optimizing protocols and analyzing integration patterns.

Molecular Therapy Advances · Jan 27, 2026Peer-reviewedMolecular Biology

A genome-scale CRISPR deletion screen in Chinese Hamster Ovary cells reveals essential regions of the coding and non-coding genome

Federico De Marco, Ivy Rose Sebastian, Antonino Napoleone, Alexander Molin, Markus Riedl, Nina Bydlinski, Krishna Motheramgari, Mohamed K. Hussein, Lovro Kramer, Thomas J. Kelly, Thomas Jostock, Nicole Borth

This study uses a genome-scale CRISPR deletion screen in CHO cells to identify essential genomic regions, revealing 427 previously unannotated or poorly characterized regions critical for cell survival.

Metabolic Engineering · Aug 19, 2025Peer-reviewedCell Biology