ImmunologybioRxivPreprint
APOE4 Drives Uniquely Dysfunctional Human Microglial States in Alzheimer's Disease
Rachel Ee, Meelad Amouzgar, Jumana Afaghani…·Sean C. Bendall
This study identifies APOE4/4-driven dysfunctional microglial states in Alzheimer's disease through multiomic analysis, revealing shifts toward terminal states with metabolic disruption and inflammatory signaling.
DOI 10.64898/2026.06.18.733295