Cancer BiologybioRxivPreprint
ABCB1-Mediated Drug Efflux Drives Resistance to VpreB1-Targeted Antibody-Drug Conjugates in B-cell Lymphoblastic Leukemia
Robin L. Williams, Xiaohong Wang, Jason Ostergaard…·Peter M. Gordon
This study identifies ABCB1-mediated drug efflux as a mechanism of resistance to VpreB1-targeted antibody-drug conjugates in B-cell lymphoblastic leukemia and suggests strategies to overcome this resistance.
DOI 10.64898/2026.08.24.746792