Cell BiologybioRxivPreprint
Depletion of microenvironmental syndecan-2 impairs hematopoietic stem cell self-renewal and cytokine responses
Matthew W. Hagen, Nicollette J. Setiawan, Rachel Wellington…·Christina Marie Termini
This study shows that syndecan-2 in mesenchymal stromal cells, but not endothelial cells, supports HSC self-renewal and cytokine responses by modulating growth factor signaling.
DOI 10.1101/2025.11.07.687077