Synthetic BiologyACS Synthetic BiologyPeer-reviewed
Design-Build-Test-Learn guided engineering of a whole-cell pyruvate biosensor based on transcription factor
Zihan Gao, Maria Suarez Diez, Pieter Candry
The paper develops a pyruvate biosensor in E. coli using Design-Build-Test-Learn cycles, achieving improved dynamic range and reduced leaky expression.
DOI 10.1021/acssynbio.5c00650