Author

Sayyam Shah

University Health NetworkORCID 0009-0005-1064-3223Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 3 Research Focus:clustering· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

Andy G.X. ZengiD· 3 shared John Edgar DickiD· 3 shared Charles Grenfell MullighaniD· 2 shared Ilaria IacobucciiD· 2 shared Qingsong GaoiD· 2 shared A. J. MurisoniD· 1 shared Airen Zaldívar PerazaiD· 1 shared Alex Murison· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCancer Biology

Andy G.X. ZengORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyNature CancerPeer-reviewedJun 27, 2025

Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia

Ilaria Iacobucci, Andy G.X. Zeng, Qingsong Gao…·Charles Grenfell Mullighan

This study uses scRNA-seq to analyze B-ALL samples, revealing transcriptional heterogeneity and developmental origins, with specific subtypes associated with distinct cell populations and clinical outcomes.

53 citationstop 1%

humanscRNA-seq

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Cell BiologybioRxivPreprintJun 11, 2025

ATP2B1 expression identifies human hematopoietic stem cells across ontogeny with superior repopulation and self-renewal capacity

Angelica Varesi, Murtaza S. Nagree, Isabella Di Biasio…·Stephanie Zhi-Juan Xie

The paper identifies ATP2B1 as a marker for human LT-HSC subpopulations with distinct repopulation and self-renewal capacities across ontogeny.

1 citation

humanscRNA-seq

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Cancer BiologyBlood Cancer DiscoveryPeer-reviewedApr 28, 2025

Single-cell transcriptional mapping reveals genetic and non-genetic determinants of aberrant differentiation in AML

Andy G.X. Zeng, Ilaria Iacobucci, Sayyam Shah…·John Edgar Dick

The paper constructs a reference atlas of human hematopoiesis and maps AML differentiation patterns, revealing genetic and non-genetic factors driving aberrant differentiation in leukemia.

134 citationstop 1%

humanscRNA-seq

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