Author

Hongbo Zhang

ORCID 0009-0005-1780-1968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:protein structure· 2 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Bo HuangiD· 2 shared Qingbo Xu· 2 shared Wenbiao ZhouiD· 2 shared Xiaoman WangiD· 2 shared Bin XiiD· 1 shared Bowen ZhangiD· 1 shared Fan FaniD· 1 shared Feng ZhouiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Bo HuangORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedFeb 7, 2026

Assessing Conformation Validity and Rationality of Deep Learning-Generated 3D Molecules

Fan Fan, Bin Xi, Xianghu Meng…·Bo Huang

This paper introduces a two-stage method to evaluate 3D molecule conformations generated by AI, achieving high speed and quantum mechanical accuracy.

2 citations

protein structuredeep learning

𝕏 PostBluesky

BioinformaticsCommunications ChemistryPeer-reviewedAug 22, 2023

Using macromolecular electron densities to improve the enrichment of active compounds in virtual screening

Wenzhi Ma, Wei Zhang, Yuan Le…·Bo Huang

This paper introduces ExptGMS, a method using experimental electron density data to improve virtual screening by enhancing active compound enrichment, achieving a 20% improvement and identifying new inhibitors.

10 citations

protein structureexperimental assay

𝕏 PostBluesky