Author

Shi-Meng Gong

Zhejiang UniversityORCID 0009-0005-3737-158XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Damiano Burrato· 1 shared Ruhong ZhouiD· 1 shared Teng Xie· 1 shared Yaqi Fu· 1 shared

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2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Damiano Burrato

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintOct 3, 2025

Design of TCR-mimicking binders for pHLA with high potency

Teng Xie, Yaqi Fu, Shi-Meng Gong…·Ruhong Zhou

The paper designs high-specificity binders for pHLA complexes using a deep learning and simulation framework, achieving nanomolar potency and mutation selectivity.

DOI 10.1101/2025.10.03.680404

humanprotein structure

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