GenomicsbioRxivPreprint
Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and Atherosclerosis
Paul-Lennard Mendez, Lion VA Raaz, Jerome Jatzlau…·Petra I. Knaus
This study identifies SMAD/FOXO1 complexes that mediate EndoMT in response to atheroprone flow, showing their role in atherosclerosis and suggesting targeting this interaction could reduce disease progression.