Author

Alex Richard-St-Hilaire

Centre Hospitalier Universitaire Sainte-JustineORCID 0009-0005-4718-0007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1

Frequent Co-Authors

Daniel SinnettiD· 2 shared Arnaud DroitiD· 1 shared Charles Joly Beauparlant· 1 shared Claire FuchsiD· 1 shared Damien FauryiD· 1 shared Élie HaddadiD· 1 shared Emeric TexeraudiD· 1 shared Emilie Ollame-Omvane· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

Daniel SinnettORCID

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3 papers

Recent·Most cited

ImmunologyCancer Immunology ImmunotherapyPeer-reviewedAug 3, 2026

TRAIL orchestrates ThINKK-induced NK cell cytotoxicity against childhood acute lymphoblastic leukemia

Emilie Ollame-Omvane, Leila Ben Khemis, Paulo Cordeiro…·Michel Duval

This study investigates how ThINKK-stimulated NK cells kill ALL cells via TRAIL and identifies TRAIL receptor expression as a biomarker for treatment sensitivity.

DOI 10.1007/s00262-026-04502-z

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintOct 7, 2025

Unveiling the temporal impact: Exploring dynamic changes in the paediatric solid tumour immune microenvironment through time

Virgile Raufaste-Cazavieille, Stéphanie Bianco, Lara Herrmann…·Raoul Santiago

This study examines the dynamic changes in the immune microenvironment of paediatric solid tumours over time, revealing a shift toward immunosuppressive and tolerogenic states.

DOI 10.1101/2025.10.07.680325

humanbulk RNA-seq

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GeneticsGenome Biology and EvolutionPeer-reviewedJan 1, 2024

Signatures of co-evolution and co-regulation in the CYP3A and CYP4F genes in humans

Alex Richard-St-Hilaire, Isabel Gamache, Justin Pelletier…·Julie Hussin

This study identifies co-evolution and co-regulation in CYP3A and CYP4F genes across human populations, linking genetic diversity to drug metabolism and health outcomes.

6 citations

humanDNA methylation

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