Author

Irina Cheng

Northwestern UniversityORCID 0009-0005-4977-1310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:Hi-C· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Cheng-Kai ShiauiD· 1 shared Galina GritsinaiD· 1 shared Jindan YuiD· 1 shared Jonathan C. ZhaoiD· 1 shared Juan WangiD· 1 shared Lina LuiD· 1 shared Martin George SandaiD· 1 shared Nicolas AltemoseiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Cheng-Kai ShiauORCID

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1 paper

Recent·Most cited

Cancer BiologyNature GeneticsPeer-reviewedJul 21, 2025

Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer

Xiaodong Lü, Viriya Keo, Irina Cheng…·Jindan Yu

This study identifies NKX2-1-driven epigenetic and 3D chromatin remodeling as key to neuroendocrine prostate cancer progression and reveals CBP/p300 inhibitors as potential therapeutic targets.

35 citationstop 1%

humanHi-C

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