Cancer BiologybioRxivPreprint
Discovery of an NRAS isoform and activation-state selective macrocyclic peptide
Kenneth K. Hallenbeck, Yunpeng Zhou, Hubert B. Josien…·S. Adrian Saldanha
The paper identifies a macrocyclic peptide that selectively binds NRAS with isoform and activation-state specificity, but lacks membrane permeability and functional inhibition.
DOI 10.64898/2026.07.30.741788