Kendra S Ziegler

This study identifies genetic loci associated with opioid use disorder-related behaviors in rats using a genome-wide association approach and network-based clustering.

The paper describes a cost-effective, high-throughput genotyping method for heterogeneous stock rats using low-coverage sequencing data, achieving high accuracy comparable to high-coverage sequencing.

The paper genotypes Y and mitochondrial chromosomes in heterogeneous stock rats and finds no significant associations with complex traits, except for gene expression on these chromosomes.

This study identifies genetic loci associated with delay discounting in Heterogenous Stock rats using GWAS, implicating Slc35f1 and Adgrl3 as potential genes involved in this behavior.