Author

Alexandria C. Fiorenza

University of Colorado BoulderORCID 0009-0005-6990-1952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Karolin LugeriD· 1 shared Mahika Anand· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBiochemistry

Karolin LugerORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 25, 2026

PARP1 Exhibits an Enzymatically Inactive Chromatin Binding Mode

Alexandria C. Fiorenza, Mahika Anand, Karolin Luger

This study identifies an enzymatically inactive chromatin binding mode of PARP1 that compacts undamaged chromatin without triggering catalytic activation.

DOI 10.64898/2026.06.24.734344

humanChIP-seq

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