Author
Alnylam Pharmaceuticals (United States)ORCID 0009-0005-7004-0483Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Megha P. Subramanian, James McIninch, Ivan Zlatev…·Vasant Jadhav
This paper develops an RNAi-based rheostat to dynamically control AAV-delivered transgene expression using siRNA or shRNA and REVERSIR technology for induction.
Se‐Hyung Park, Robert Nathaniel Helsley, Taghreed Fadhul…·Samir Softic
This study shows that fructose metabolism via KHK-C increases ER stress and modulates the hepatic transcriptome, contributing to NAFLD progression in both genetic and diet-induced models.
Margaret M. Parker, Scott M. Damrauer, Catherine Tcheandjieu…·Paul Nioi
This study identifies a significant association between the V122I TTR variant and polyneuropathy in Black individuals, highlighting increased risk of hATTR amyloidosis manifestations.