Author
University of WaterlooORCID 0009-0005-7146-6988Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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The paper simulates the diurnal effects of diuretics on renal transporters in normotensive and hypertensive kidneys, showing time-of-day differences in natriuresis, diuresis, and kaliuresis.
This study develops a mathematical model to differentiate types of drug resistance and evaluates treatment strategies, finding that bolus injection can extend survival at equivalent cumulative dosages.
This study develops sex-specific computational models to analyze how diuretics affect renal electrolyte transport differently in male and female rats under hypertension.