Author

Ankur Chattopadhyay

Indian Institute of Technology KanpurORCID 0009-0005-7365-5715Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Appu Kumar SinghiD· 1 shared Kirill A. MartemyanoviD· 1 shared KV Nageswar· 1 shared Mansi SharmaiD· 1 shared Nishtha Varshney· 1 shared Rohit Chettri· 1 shared SRISTI NANDA· 1 shared Vikesh KumariD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Appu Kumar SinghORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintFeb 18, 2026

Unique pore architecture underlies constitutive gating of human retinalTRPM1

Mansi Sharma, KV Nageswar, Vikesh Kumar…·Appu Kumar Singh

The paper reports the first cryo-EM structure of human TRPM1 in a conducting state, revealing an unexpected domain-swapped pore architecture and constitutive gating mechanism.

DOI 10.64898/2026.02.18.706614

humancryo-EM

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