Author

Daniel Salamonsen

UiT The Arctic University of NorwayORCID 0009-0005-8550-2775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher FröhlichiD· 2 shared Daojiong WangiD· 2 shared Karol BudaiD· 2 shared Marc W. van der KampiD· 2 shared Andrea PierangeliniiD· 1 shared H. Adrian BunzeliD· 1 shared Kinga Virág Gulyás· 1 shared Nobuhiko TokurikiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Christopher FröhlichORCID

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2 papers

Recent·Most cited

Molecular BiologyJournal of Molecular BiologyPeer-reviewedJun 5, 2026

Mechanistic origins and evolutionary erosion of collateral sensitivity in a β-lactamase

Daniel Salamonsen, Karol Buda, Daojiong Wang…·Christopher Fröhlich

This paper investigates the molecular mechanisms of collateral sensitivity in β-lactamase evolution, showing how specific mutations alter enzyme structure and drug resistance profiles.

1 citation

E. coliexperimental assay

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Molecular BiologybioRxivPreprintDec 31, 2025

Evolution tunes functional sub-state interconversion to boost enzyme function

Daniel Salamonsen, Andrea Pierangelini, Karol Buda…·Christopher Fröhlich

This paper shows how evolution improves enzyme function by shifting the rate-limiting step from substrate binding to sub-state interconversion in β-lactamase OXA-48.

1 citation

protein structureprotein sequence

𝕏 PostBluesky