BioengineeringbioRxivPreprint
Restoration of tumor suppressor protein with enhanced activity using super-tRNAs to induce tumor regression
Bangyan Kong, Zhetao Zheng, Zeyuan Mi…·Qing Xia
This paper demonstrates that engineered super-tRNAs can restore and enhance tumor suppressor protein function by overcoming nonsense mutations, leading to tumor regression in xenograft models.
DOI 10.1101/2025.03.18.643282